Synthesis of Indoles via Intermolecular and Intramolecular Cyclization by Using Palladium-Based Catalysts

As part of natural products or biologically active compounds, the synthesis nitrogen-containing heterocycles is becoming incredibly valuable. Palladium a transition metal that widely utilized as catalyst to facilitate carbon-carbon and carbon-heteroatom coupling; it used in various heterocycles. This review includes twelve years successful indole using palladium catalysts establish carbon-nitrogen coupling, well conditions have been optimized.